A decline in CoQ10 concentration in an ageing heart has been connected with various cardiovascular diseases, the leading cause of morbidity and mortality in the Western world.
“CoQ10 is the first new medication to improve survival in chronic heart failure, and it should be added to standard therapy.”
Assoc. Prof. Svend Aage Mortensen, Head of the Q-symbio study.
The beneficial effects of CoQ10 supplementation in hearth health have been shown in many studies. Oral intake of CoQ10 improves functional capacity of the heart, its endothelial function and left ventricular systolic function in advanced chronic heart failure without any side effects. CoQ10 may also be safely added as an adjuvant therapy to hypertensive and angina patients.
CHOLESTEROL AND STATINS
Statins are drugs used to lower raised blood cholesterol levels, which have been associated with increased risk of heart disease. However, these drugs also influence the biosynthesis of CoQ10: its plasma levels are lowered in the course of statin treatment.
Statins competitively restrict the synthesis of mevalonate, a cholesterol precursor. However, mevalonate is also the precursor of a dozen other end-products, including CoQ10. Hence, also the synthesis of CoQ10 is interrupted. That is why majority of statin users often lacks of energy and experiences muscle aches and cramps. CoQ10 supplementation is therefore often recommended hand in hand with statins.
The accumulation of damage to the organism caused by free radicals represents an important part of the ageing process. As coenzyme Q10 is present exactly where the majority of free radicals is generated it has a fundamental impact on the ageing process.
CoQ10 is also known as elixir of youth and is thus often used in cosmetic industry. However, due to protective property of human skin, CoQ10 used in creams can hardly penetrate deeper – to the cells where it is actually needed. On the other hand, the oral intake of CoQ10 can restore its normal levels in various tissues and thus slow down the aging process and reduce its signs. Furthermore, regular oral intake of Q10Vital® has shown amazing results* in improving skin conditions, such as skin evenness and firmness, and subsequently the skin microrelief.
*Read more about the study here.
Patients with various neurodegenerative diseases have also been successfully treated with CoQ10. Q10Vital® is an excellent example of good practice in treating patients with mitochondrial diseases.
Substantial data has been gathered about the beneficial effects of CoQ10 in neurodegenerative diseases. This reflects to cases with impaired mitochondrial function and/or excessive oxidative damage, including Parkinson’s disease, Huntington’s disease and Friedreich’s ataxia. Clinical trials suggest that CoQ10 supplementation can slow down functional decline in these disorders.
“We have determined an exceptionally good acceptability of Quvital® in most children and, subsequently, an anamnestically and objectively determined improvement of clinical effects in relation to equal or higher doses of coenzymeQ10 in the form of soft gelatin capsules”
Prof. Dr. David Neubauer, MD, Head of the Department of Paediatric Neurology at the Children’s Hospital of the University Medical Centre Ljubljana
The efficiency of CoQ10 as a preventive treatment for migraine headaches was first investigated in 2002.
The average number of days with a migraine was halved after 3 months of regular therapy with CoQ10. It was further reported that a CoQ10 deficiency may be common to migraine patients, while an efficacious and well tolerated treatment was also confirmed by a randomized control trial.
MALE INFERTILITY, PERIODONTAL DISEASE, IMMUNE SYSTEM
Beneficial effects of regular Q10 intake in high doses have also been reported in the treatment of male infertility, periodontal disease, immune system support, and many other conditions.
The supplementation of Q10 can also improve the tolerability of cancer treatments. In individual cases, a partial or complete regression of cancer has also been observed in relation to Q10 supplementation.